Clinical Research Services

Transcranial Magnetic Stimulation (TMS) is a non-invasive method using magnetic fields to stimulate brain nerve cells. In clinical trials, it measures cortical excitability as biological markers to study drug effects. (TMS and Drugs, Zeimann, 2004)

Electroencephalography (EEG) is particularly well suited to Phase I clinical trials. It is a non-invasive and easy to deploy method of obtaining indications of blood brain barrier penetration and target engagement and is easily translatable from animal models. It can also be combined with other modalities to provide a more in-depth dose response and safety profile.

Cognitive tests are assessment tools used to measure various aspects of cognitive function, including memory, attention, executive function, and language skills. These tests are designed to evaluate an individual’s cognitive abilities and provide insights into shifts in their cognitive performance in relation to treatment.

Quantitative Sensory Testing (QST) is a method used to objectively measure sensory perception, including pain, in response to various stimuli (e.g., heat, cold, pressure). Incorporating QST into your clinical trial provides reliable and standardised measurements of sensory function, allowing for more accurate assessment of pain-related conditions.